{"id":3105,"date":"2022-09-09T10:25:24","date_gmt":"2022-09-09T08:25:24","guid":{"rendered":"https:\/\/www.dcfinechemicals.gmedia.ovh\/?p=3105"},"modified":"2022-09-13T14:03:24","modified_gmt":"2022-09-13T12:03:24","slug":"oxamato-de-sodio","status":"publish","type":"post","link":"https:\/\/dcfinechemicals.gmedia.ovh\/es\/oxamato-de-sodio\/","title":{"rendered":"Oxamato de sodio"},"content":{"rendered":"

En el art\u00edculo de hoy, como empresa fabricante de qu\u00edmica fina y distribuidora de productos qu\u00edmicos, hablaremos sobre el oxamato de sodio, un compuesto qu\u00edmico cuya f\u00f3rmula molecular es Na2C2O4 y f\u00f3rmula desarrollada es NaOOC-COONa.\u00a0<\/span><\/p>\n

Curiosidades y aplicaciones del oxamato de sodio<\/span><\/h2>\n

El oxamato de sodio es una forma isost\u00e9rica de piruvato, conocido tambi\u00e9n como un potente inhibidor de la lactato deshidrogenasa (LDH) y concretamente como LDH-A. Como expertos en la manipulaci\u00f3n de productos qu\u00edmicos podemos afirmar que inhibe la conversi\u00f3n de piruvato a lactato a trav\u00e9s de lactato deshidrogenasa (LDH), un hecho muy valioso y determinante en diferentes campos.\u00a0<\/span><\/p>\n

Adem\u00e1s, este oxamato de sodio induce la detenci\u00f3n del ciclo celular G2\/M, todo esto a trav\u00e9s de la regulaci\u00f3n a la baja de la v\u00eda CDK1\/ciclina B1 y promoviendo la apoptosis mediante la mejora de la generaci\u00f3n de ROS mitocondrial.<\/span><\/p>\n

Y es que, como <\/span>distribuidora de productos qu\u00edmicos<\/b><\/a> podemos afirmar que el oxamato de sodio tambi\u00e9n ha sido estudiado como un inhibidor del metabolismo de los carbohidratos en varios tumores, ya que las c\u00e9lulas cancerosas a menudo dependen de la gluc\u00f3lisis para la producci\u00f3n de ATP. Este hecho, supone un gran avance en la investigaci\u00f3n m\u00e9dica y es que como fabricante de qu\u00edmica fina siempre apoyamos cada paso que da la ciencia en el campo de la medicina y dem\u00e1s campos que puedan ayudar a mejorar la salud y nuestro entorno.<\/span><\/p>\n

Otro dato curioso del oxamato de sodio, es que este compuesto junto con un agente antidiab\u00e9tico conocido como fenformina o fenetilbiguanida, si se trabajan en conjunto poseen propiedades anticancer\u00edgenas potenciales. Un hecho que demuestra que si se hace una<\/span> correcta manipulaci\u00f3n de productos qu\u00edmicos<\/b><\/a>, junto un estudio previo, pueden dar grandes resultados en la investigaci\u00f3n de diferentes campos.\u00a0<\/span><\/p>\n

Adem\u00e1s, la fenformina cuando se administra sola, tiene una alta incidencia de acidosis l\u00e1ctica. Debido a la capacidad inherente del oxamato para prevenir la conversi\u00f3n de piruvato en lactato, puede usarse para contrarrestar los efectos secundarios de la fenformina.<\/span><\/p>\n

Asimismo, el oxamato de sodio tambi\u00e9n posee un papel inhibidor con el oxaloacetato, un intermediario importante para el ciclo del \u00e1cido c\u00edtrico. Un componente que compite y se une al sitio activo del dominio carboxil transferasa e invierte la reacci\u00f3n de descarboxilaci\u00f3n del oxaloacetato por la piruvato carboxilasa.<\/span><\/p>\n

Desde DC Fine Chemicals, como empresa fabricante de qu\u00edmica fina y distribuidora de productos qu\u00edmicos, siempre apoyamos cada paso hacia delante que da la ciencia. Y es que, ya sean productos farmac\u00e9uticos, productos sanitarios, productos para ciencias de la vida o productos sanitarios para diagn\u00f3stico estamos a su lado para todo lo que nos necesiten como especialistas en la manipulaci\u00f3n de productos qu\u00edmicos.<\/span><\/p>\n

Informaci\u00f3n t\u00e9cnica<\/span><\/h2>\n

Identification:<\/strong><\/p>\n

    \n
  • Name: Sodium oxamate<\/li>\n
  • Alternated names: Oxamic acid sodium salt, Sodium 2-amino-2-oxoacetate, Oxamic acid, sodium salt.<\/li>\n
  • CAS #: 565-73-1<\/li>\n
  • Smiles: [Na+].NC(=O)C([O-])=O<\/li>\n
  • InChI: 1S\/C2H3NO3.Na\/c3-1(4)2(5)6;\/h(H2,3,4)(H,5,6);\/q;+1\/p-1<\/li>\n
  • InChI key: RQVZIJIQDCGIKI-UHFFFAOYSA-M<\/li>\n<\/ul>\n

    Properties:<\/strong><\/p>\n

      \n
    • Molecular formula: C2<\/sub>H2<\/sub>NNaO3<\/sub><\/li>\n
    • Molecular weight: 111.03<\/li>\n
    • Appearance: white solid<\/li>\n
    • Melting point: > 300\u00ba C<\/li>\n
    • Assay (T): 98-102%<\/li>\n
    • Solubility: H2<\/sub>O, 25 mg\/mL, clear, colourless<\/li>\n<\/ul>\n

      Storage conditions:<\/strong><\/p>\n

        \n
      • Store in cool place at 10\u00b0C – 25\u00b0C. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

        En el art\u00edculo de hoy, como empresa fabricante de qu\u00edmica fina y distribuidora de productos qu\u00edmicos, hablaremos sobre el oxamato […]<\/p>\n","protected":false},"author":3,"featured_media":3108,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[46],"tags":[],"yoast_head":"\nOxamato de sodio | DC Fine Chemicals<\/title>\n<meta name=\"description\" content=\"Conoce las propiedades y los componentes que forman el oxamato de sodio en este art\u00edculo. \u00a1Te esperamos en DC Fine Chemicals!\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Oxamato de sodio | DC Fine Chemicals\" \/>\n<meta property=\"og:description\" content=\"Conoce las propiedades y los componentes que forman el 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